# INTRODUCTION From the moment of their existence, animals exhibit innate and acquired behaviors. Innate behavior; is an instinctive stereotyped movement pattern or reflex-type behavior that occurs due to a stimulus without the need for experience (Aydemir and Bilge 2022). For example, the female animal suckling her young after pregnancy. Apart from this, it is observed that animals exhibit behaviors such as the defense of the area, competition behaviors, and communication in social groups. It is observed that they exhibit various behaviors for temporary periods that occur under the influence of illness, pain, and medication. But; as a result of factors such as anxiety and stress, they exhibit abnormal behaviors such as phobia (Aydemir and Bilge 2022). Such behaviors are passed down through generations through genes specific to the species. In many behaviors, it can be acquired later with environmental adaptations (Aydemir and Bilge 2022). Apart from the normal behavior typical of all animals species; aggression behaviors in line with environmental effects such as fear, different light wavelengths, different sound frequencies, heat, stress (status-related attack, intermale attack), predatory attack, idiopathic anger attack (idiopathic rage), fear-based attack (fear-induced), territorial and instinctive attack (maternal), environmentally damaging behaviors, coprophagia, social behavior and agonistic behaviors, urination or defecation outside the designated place, urine marking, wool (cloth) sucking, abnormal behaviors such as aggression are exhibited (Sambraus 1998 Thanks to the electroencephalography obtained from these behavioral disorders, it is possible to comment on the relations between the species. # III. DISCUSSION When many studies on animals and humans are examined; is observed that there is a close relationship between the emotional states of animals and humans. As an indicator of this close relationship; is stated that facial expressions in mice reflect internal emotional states, just like facial expressions in humans (Dolensek et # Mood # Brittlebank et al. (1993) in the results of a study; In the case of depression, people are prejudiced against overgeneralization; reported that animals exhibit simple behaviors such as avoidance and approach as an indicator of their internal emotional state. In the results of another study, Grandjean et al. (2016) determined that increased amygdala-PFC functional connectivity and white matter structural changes in the cingulum showed similarity in mice and humans against chronic stress. The results of a study by Xunxun Chu (2019) reported that the naturally induced depression models in macaques are very similar to the human depression model. # Sleeping Disorder When examining studies on sleep disorders, Gadad et al. (2013) and Crawley (2012) reported in the results of the study that there is a similarity between the symptoms of sleep disorders between animal models and humans. According to Jaramillo et Andersen and Tufik (2003), in the results of the studies against a living thing that affects from the outside; observed that they exhibit temporary or permanent changes in behavior. Moreover; they also found that their mice showed sleep disorders. Armitage (2007) found in a study that electroencephalography findings were more than 80% of patients with depression and that these people had sleep disorders. # Epilepsy # Genetic Among the factors affecting behavior in model animals; genetic factors, age, gender, physiological, and hormonal conditions are included. In the results of a study using mice as model animals, Cambiaghi et al. (2012) reported that tuberous sclerosis complex caused by benign tumors in different organs and serious neuropsychiatric symptoms such as epilepsy, intellectual disability, autism, anxiety, and depressive behavior can be determined by EEG method. Also, Cambiaghi et al. (2012) found that anxiety and depression were reduced in mutant mice treated with rapamycin in their EEG power spectrum results. Carter (1978) reported that it produced a trance-like stupor in all monkeys associated with marked EEG changes and hypothermia in adult and preadolescent rhesus monkeys. Researchers have also found that characteristic EEG and behavioral changes are age-related. In another study, Cai et al. (2020) examined expression networks, locomotive, and cognitive behaviors, and EEG and gene-circuit-behavior analyses in genetically modified monkeys. The results of the study; reported that decreased ?-synchronization in front-parietal-occipital networks was associated with abnormal locomotive behaviors. Blackburn-Munro (2004), who conducted a study on genetically manipulated animals, stated that there are many pathological changes similar to various chronic pain in humans in animal models of chronic pain, using it together with classical physiological and biochemical measurements according to EEG results. Moreover; reported that the evaluation of pain and stress with the EEG method in animals is an alternative method. Tuberous sclerosis Complex is a multisystem genetic disorder caused by mutations in the Tsc1 or Tsc2 genes that lead to hyperactivation of the London Journal of Engineering Research # 22 Electroencephalography in Determining Mood in Animals They also stated that low alpha synchronization due to thirst after drinking, which is created not only by water consumption but also by surrogate m TOR pathway, a key signaling pathway for synaptic plasticity. # Pain Joyce and David (2019), who conducted a study on rats, mice, and monkeys, examined the electroencephalography of acute and chronic pain. In the results of the study, the researchers observed that the transition from acute pain to chronic pain resulted in significant changes in brain function. Moreover; they reported that brain activations in acute pain are related to the sensory aspect of noxious stimuli, including the primary somatosensory cortex, insula, cingulate cortex, thalamus, retrosplenial cortex, and periaqueductal gray. In the results of the study, they stated that the human acute pain model can be applied to sheep and that these electroencephalogram changes can provide a good measure for acute pain in sheep. They reported that these relationships are a frugal indicator between EEG data and behavior. They found a slight but significant reduction in theta and alpha mean dominant frequency (MDF) with behavioral changes in rapamycin-treated wild-type mice, suggesting a mild brain dysfunction associated with the drug treatment studies by Salinsky et al. (2004), Leocani et al., (2000Leocani et al., ( , 2010)), Klimesch (1999), and Klimesch, (1997). They reported that this resulted in a mild brain dysfunction associated with drug therapy. They also observed that EEG slowing in humans is associated with neurological disorders or even lower working memory, IQ or drug-induced lethargy, and cognitive impairment in healthy subjects. # Dependence Howard (2000) examined the electroencephalography of the brain functioning in various animal models with alcohol dependence. The researcher reported that there are physiological and behavioral advantages and disadvantages to alcohol withdrawal syndrome. The researcher also stated that it may affect enhanced autonomic nervous system activation, sensory hyperreactivity, convulsions, anxiety, and dysphoria. When other similar studies are examined, Walker and Zornetzer (1974), Ehlers and Chaplin (1991), Poldrugo and Snead (1984), and Perrin et al. (1975) reported that EEG abnormalities were associated with alcohol withdrawal in various model animals, including mice, rats, cats, and primates. # IV. CONCLUSIONS There are various behaviors that they exhibit depending on the various moods observed in humans and various model animals. ![Ong et al. (1997) measured acute pain in sheep and examined changes in both the electroencephalogram frequency spectrum and behavioral responses to increased electrical stimulation in sheep.](image-2.png "") ![37. MedicineVanLier et al. (2004), Graversen et al. (2012) Leocani et al. (2000), and Barry et al. (2009); In the studies conducted by Cambiaghi et al. (2012) Baumann et al. (2006) stated that the changes in the brain caused by the drug efficacy in humans and animal models are closely related to behavior.](image-3.png "") activities in the brain (Ward 2013-2015; Bear etal. 2016; Lopes and MEG 2013). Thanks to thismethod, information is obtained about normaland abnormal functioning in the brain.Electroencephalography reflects the total slowdendritic potentials of many cortical pyramidalAll these behaviors exhibited are a psychologicalneurons. EEG rhythms in different frequencyindicator of the emotional state of the animalbands arise from dynamic interactions between(Bilge and Aydemir 2022; Aydemir and Bilgepopulations of neurons and are associated with2022; Aydemir et al. 2021). These psychologicalseveral different cognitive processes. With thisindicators are very similar to humans. Forassociation, EEG recordings show abnormalitiesexample; Behaviors such as depression, socialin brain functioning (Ward 2013-2015; Bear et al.avoidance, anhedonia, passive coping, and2016; Lopes and MEG 2013).learned helplessness observed in humans aresimilar to the behaviors exhibited in animals (TyeIt has also been used in the diagnostic criteria of2018; Muir et al. 2018). Moreover; is observedvariouspsychiatricdisorderssuchasthat many model animals such as mice andschizophrenia, bipolar disorder, sleep disorder,monkeys exhibit similar behaviors in manyattention-deficit/hyperactivity disorder (ADHD),diseases such as depression, chronic stress, sleepand Alzheimer's disease, especially in recent yearsdisorders, and epileptic seizures observed in humans (Brittlebank et al. 1993; Grandjean et al. 2016; Gadad et al. 2013) and Crawley 2012; According to Jaramillo et al. 2016; Dhamne et al. 2017; Citraro et al. 2019; Roebuk et al. 2020; According to Cai et al. 2020; According to Gandal et al. 2010; Dringenberg 2000). This gives information about the behavior between humans and animals. Various behavioral tests, biomarkers, and Electroencephalograms are used to measure this information (Roach et al. Mathalon, 2008; Koenig et al., 2005). Electroencephalograms (EEG) are a non-invasive technique that allows the measurement of electrical brain activity in a human or model animal. It can also record brain signals thanks to its high temporal resolution (Ward 2003; Lopes(Roach et al. Mathalon, 2008; They observed that repetitive grooming, socialand MEG 2013). These recorded signals are adeficits, decreased activity, anxiety, learninggood source for obtaining information about theproblems, reduced fear conditioning, olfactoryneurological status of the model creature (Saminudisorders, hyperactivity, and various autistic-likeet al., 2021).behavioral disorders occur in the model animal(Jaramillo et al. 2016; Dhamne et al. 2017;II. ELECTROENCEPHALOGRAPHY (EEG) INBalzamo). et al. 1998; Gadad et al. 2013; CrawleyMODEL ANIMALS2012Electroencephalography in model animals is amethod used to functionally examine the electricalsignals produced as a result of neurological ; Cao et al. 2020; Radyushkin et al. 2009; Liu et al. 2017). London Journal of Engineering Research 20 Electroencephalography in Determining Mood in Animals (2003), Neurodevelopmental disorders, mood disorders, olfactory disorders, visual attention dysfunction, sleep disorders, brain dysfunction, learning disorders, various adjustment, and autistic-likeLondon Journal of Engineering Researchbehavior disorders, autism, attention deficit,hyperactivity, anxiety, aging, traumatic braininjury in various model animals. It has beenobserved that various behaviors such as repetitivegrooming, social deficits, decreased activity,anxiety, fear conditioning, calmness, staring,anxiety, fear, learning disability, intermodalrecognition memory and depression are exhibited. 23 Electroencephalography in Determining Mood in Animals It has been observed that these behaviors closely resemble each other among various species of electroencephalography. Electroencephalography in Determining Mood in Animals * Sleep patterns over 21-day period in rats with chronic constriction of sciatic nerve MLAndersen STufik Brain Res 984 2003 * Sleep and circadian rhythms in mood disorders RArmitage Acta Psychiatrica Scandinavica 115 2007. s433 * Animal Psychology-BEHAV?OR AND TEM-PERAMENT IN CATS AND DOGS EAydemir ?Bilge 2022 LAP LAMBERT Academic Publishing -ISBN * Emotional expressions reconsidered: Challenges to inferring emotion from human facial movements LFBarrett RAdolphs SMarsella AMMartinez SDPollak Psychol. Sci. Public Interest 20 2019 * Acute atomoxetine effects on the EEG of children with attention-deficit/ hyperactivity disorder RJBarry ARClarke MHajos RMc Carthy MSelikowitz JMBruggemann Neuro-pharmacology 57 2009 Dec * Sleep EEG changes after middle cerebral artery infarcts in mice: different effects of striatal and cortical lesions CRBaumann EKilic BPetit EWerth DMHermann MTafti CLBassetti Sleep 29 2006 * Scoring of sleep and wakefulness by behavioral analysis from video recordings in rhesus monkeys:comparison with con-ventional EEG analysis EBalzamo PVan Beers DLagarde Electroencephalogr. Clin. Neurophysiol 106 3 1998 * Neuroscience: Exploring the Brain MFBear BWConnors MAParadiso Neuroscience: Exploring the Brain: Fourth Edition 223 2016 Wolters Kluwer Philadelphia * Model sofhuman sleepregulation DGBeersma Sleep: physiology, investigations and medicine Billiar Dm New York Kluwer Academic/Plenum Publishers 2003 * Interpretation Of The Relationship Between The Effects Of Different Colors Wavelength Light Application And Sound Frequency In Japanese ?Bilge EAydemir Quails By Spectral Analysis. Techno-Science 4 2021 * T?me-Frequency Analys?s And Exam?nat?on Of Responses To D?fferent Color Waves Depend?ng On Sex In Japanese Qua?ls ?Bilge EAydemir Behav?or And Adaptat?on W?th An?mal Sound 2022 Lap Lambert Academic Publishing * ?Bilge EAydemir 2022 * Comportement Et Adaptation Avec Le Son Animal-CaillesJaponaises Editions Notre Savoir 2022-04-27 * Pain-like behaviours in animals -how human are they? GBlackburn-Munro Trends in Pharmacological Sciences 25 6 2004 * An overview of types of agressive behaviour in dogs and methods of treatments JKBlackshaw Appl. Anim. Behav. Sci 30 1991 * Normal polysomnography parameters in healthy adults: a systematic review and meta-analysis MIBoulos TJairam TKendzerska JIm AMekhael BJMurray Lancet Respir. Med 7 2019 * Autobiographical memory in de-pression: state or trait marker? ADBrittlebank Br. J. Psychiatry 162 1993 * MECP2 Duplication Causes Aberrant GABA Pathways, Circuits and Behaviors in Transgenic Monkeys: Neural Mappings to Patients with Autism D.-CCai ZWang TBo SYan YLiu ZLiu ZWang The Journal of Neuroscience 40 19 2020 * EEG and subjective sleepiness during extended wakefulness in seasonal affective disorder: circadian and homeostatic influences CCajochen DPBrunner KKrauchi PGraw AWirz-Justice Biol Psychiatry 1 7 2000 * Behavioural and EEG effects of chronic rapamycin treatment in a mouse model of Tuberous Sclerosis Complex MCambiaghi MCursi LMagri VCastoldi GComi FMinicucci LLeocani Neuropharmacology 67 2013 * Thermography as a Non-Invasive Measure of Stress and Fear of Humans in Sheep SCannas CPalestrini ECanali BCozzi NFerri EHeinzl MMinero MChincarini GVignola EDCosta 2018 8 146 * Neuroligin 2 regulates absence seizures and behavioral arrests through GABAergic transmission within the thalamocortical circuitry FCao JJLiu SZhou MACortez OCSnead JHan Nat. Commun 11 3744 2020 * Evaluation of the effects of liraglutide on the development of epilepsy and behavioural alterations in two animal models of epileptogenesis RCitraro MIannone ALeo CDe Caro VNesci MTallarico ERusso 10.1016/j.brainresbull.2019.08.001 Brain Research Bulletin 153 2019 * Sleep wake profile and EEG spectral power in young or old senescence accelerated mice DColas RCespuglio NSarda Neurobiol. Aging 26 2 2005 Feb * Translational animal models of autism and neurodevelopmental disorders JNCrawley Dialog. Clin. Neurosci 14 2012 * Consensus clinical guidelines for the assessment of cognitive and behavioural problems in tuberous sclerosis PDe Vries AHumphrey DMccartney PPrather PBolton AHunt Eur. Child. Adolesc. Psychiatry 14 2005 * Replicable in vivo physiological and behavioral phenotypes of the Shank3B null mutant mouse model of autism SCDhamne JLSilverman CESuper SH TLammers MQHameed MEModi Mol. Autism 8 26 2017 * Facial expressions of emotion states and their neuronal correlates in mice NDolensek Science 368 2020 * Alzheimer's disease: more than a 'cholinergic disorder'-evidence that cholinergic-monoaminergic interactions contribute to EEG slowing and dementia HCDringenberg Behav. Brain Res 115 2 2000 * EEG and ERP response to chronic ethanol exposure in rats CREhlers RIChaplin Psychopharmacology 104 1991 * Hippocampal dysfunction after lateral fluid percussion injury MFedor RFBerman JPMuizelaar BGLyeth J. Neurotrauma 27 2010 * Neuropathology and animal models of autism: genetic and environmental factors BSGadad LHewitson KAYoung DCGerman Autism Res. Treat 731935 2013. 2013 * Validating ? oscillations and delayed auditory responses as translational biomarkers of autism MJGandal JCEdgar RSEhrlichman MMehta TPRoberts SJSiegel Biol. Psychiatr 68 12 2010 * Biomarkers in psychiatry: concept, definition, types and relevance to the clinical reality MSGarcía-Gutiérrez Front. Psychiatry 11 432 2020 * Effect of low-level, low-frequency electric fields on EEG and behavior in Macaca nemestrina RJGavalas DOWalter JHamer WRossadey 10.1016/0006-8993(70)90132-0 Brain Research 18 3 1970 * Light therapy for seasonal affective disorder with blue narrow-band light-emitting diodes (LEDs) GGlickman BByrne CPineda WWHauck GCBrainard Biol Psychiatry 15 6 2006 * Chronic psychosocial stress in mice leads to changes in brain functional connectivity and metabolite levels comparable to human depression JGrandjean Neuroimage 142 2016 * The analgesic effect of pregabalin in patients with chronic pain is reflected by changes in pharmaco-EEG spectral indices CGraversen SSOlesen AEOlesen KSteimle DFarina OHWilder-Smith SABouwense HVan Goor AMDrewes Br. J. Clin. Pharmacol 73 3 2012 * Electroencephalography in Determining Mood in Animals 39. Howard C. B., 2000. Animal Models Of Alcohol Withdrawal MHallaschmid MMölle SFischer JBorn Alcohol Research & Health 113 2002 Clinical Neurophysiology. * Altered striatal synaptic function and abnormal behaviour in Shank3 Exon4-9 deletion mouse model of autism TCJaramillo HESpeed ZXuan JMReimers SLiu CMPowell 10.1002/aur.1529 Autism Res 9 2016 * Neuroimaging of pain in animal models: a review of recent literatüre TDaJoyce DavidSilva Seminowicz Pain Reports 4 4 732 2019 * MAKheirbek RHen New neurons in the brain keep anxiety at bay. Sci. Am. Published online July 2014 * Neurogenesis and generalization: a new approach to stratify and treat anxiety disorders MAKheirbek Nat. Neurosci 15 2012 * Competing roles of slow oscillations and delta waves in memory consolidation versus forgetting JKim TGulati KGanguly 2019 179 514.e3-526.e3 * EEG-alpha rhythms and memory processes WKlimesch Int. J. Psychophy-siol 26 340 1997 IQ * EEG alpha and theta oscillations reflect cognitive and memory performance: a review and analysis WKlimesch Brain Res. Cogn. Brain Res. Rev 29 2e3 1999 * Decreased EEG synchronization in Alzheimer's disease and cognitive impairment TKoenig LPrichep TDierks DHubl LOWahlund ERJohn VJelic Neurobiol., Aging 26 2 2005 * Positive and negative emotions in dairy cows: Can ear postures be used as a measure? HLambert GCarder Behav. Process 158 2019 * Electroencephalographic signatures of pain and analgesia in rats BWLeblanc PMBowary YCChao TRLii CYSaab 2016 157 * Neurophysiological correlates of cognitive disturbances in multiple sclerosis LLeocani JJGonzalez-Rosa GComi Nov Neurol. Sci 31 2010 Suppl. 2 * Electroencephalographic coherence analysis in multiple sclerosis: correlation with clinical, neuropsychological, and MRI find-ings LLeocani TLocatelli VMartinelli MRovaris MFalautano MFilippi GMagnani GComi J. Neurol. Neurosurg. Psychiatr 69 2 2000. Aug * Neuroligin 3 R451C mutation alters electroencephalography spectral activity in an animal model of autism spectrum disorders JJLiu KPGrace RLHorner MACortez YShao ZJia Mol. Brain 10 2017 * EEG and MEG: Relevance to Neuroscience FLopes Da Silva Neuron 80 2013 * Sustained activation of mTOR pathway in embryonic neural stem cells leads to develop-ment of tuberous sclerosis complex-associated lesions LMagri MCambiaghi MCominelli CAlfaro-Cervello MCursi MPala ABulfone JMGarcia-Verdugo LLeocani FMinicucci Cell Stem Cell 9 2011 * The development and use of facial grimace scales for pain measurement in animals JSMogil DSPang GG SDutra CTChambers Neurosci. Biobehav. Rev 116 2020 * A subpopulation of rats show social and sleep-waking changes typical of chronic neuropathic pain following CRMonassi 2003 * Peripheral nerve injury Eur. J. Neurosci 17 * Brain imaging of pain: state of the art DLMorton JSSandhu AKJones J Pain Res 9 2016 * Wiring the depressed brain: optogenetic and chemogenetic circuit interrogation in animal models of depression JMuir Neuropsychopharmacology 44 1013 2019 * Multidimensional predictors of suscep-tibility and resilience to social defeat stress CNasca Biol. Psychiatry 86 2019 * Snead Gamma Hydroxybutyrate ?n The Monkey, I., 1978. Electroencephalographic, Behavioral, And Pharmacokinetic Studies Neurology OCarter July 1 First Published * From pillow to podium: a review on understanding sleep for elite athletes SO'donnell CMBeaven MWDriller 10.2147/nss.s158598 Nat. Sci. Sleep 10 2018 * Behavioural and EEG changes in sheep in response to painful acute electrical stimuli ROng JMorr?s JO'dwyer JBarnett PHemsworth IClarke Australian Veterinary Journal 75 3 1997 * 10.1111/j.1751-0813.1997.tb1006 193 * Contactless monitoring of heart and respiratory rate in anesthetized pigs using infrared thermography CBPereira HDohmeier JKunczik NHochhausen RTolba MCzaplik PLoS ONE 14 224747 2019 * Electroencephalographic signs of ethanol tolerance and physical dependence in the cat RGPerrin HKalant KELivingston Electroencephalography and Clinical Neurology 39 1975 * Electroencephalographic and behavioral correlates in rats during repeated ethanol withdrawal syndromes FPoldrugo OCSnead Psychopharmacology 83 1984 * Neuroligin-3-deficient mice: model of a monogenic heritable form of autism with an olfactory deficit KRadyushkin KHammerschmidt SBoretius FVaroqueaux AEl-Kordi ARonnenberg 10.1111/j.1601-183x.2009.00487 Genes Brain Behav 8 2009 * BJRoach DHMathalon 2008 * Event-related EEG time-frequency analysis: an overview of measures and an analysis of early gamma band phase locking in schizophrenia Schizophr. Bull 34 5 * Cognitive Impairments in Touchscreen-based Visual Discrimination and Reversal Learning in Genetic Absence Epilepsy Rats from Strasbourg AJRoebuck LAn WNMarks NSun TPSnutch JGHowland Neuroscience 430 2020 * Effects of oxcarbazepine and phenytoin on the EEG and cognition in healthy volunteers MSalinsky DSpencer BOken DStorzbach Epilepsy Behav 5 2004 * Aufgaben der Angewandten Ethologie bei Landwirtschaftlichen Nutztieren fr herund heute HHSambraus Gumpensteiner Tagung "Nutztierhaltung im Wandel der Zeit A-8952 Irdning 2002 * A Recent Investigation on Detection and Classification of Epileptic Seizure Techniques Using EEG Signal SSaminu GXu ZShuai IAbd El Kader AHJabire YKAhmed IAKaraye ISAhmad Brain Sciences 668 2021 * The hippocampus is crucial for forming non-hippocampal long-term memory during sleep ASawangjit CNOyanedel NNiethard CSalazar JBorn MInostroza 10.1038/s41586-018-0716-8 Nature 564 2018 * Complex interaction of circadian and non-circadian effects of light on mood: Shedding new light on an old story KMStephenson CMSchroder GBertschy PBourgin 10.1016/j.smrv.2011.09.002 Sleep Medicine Reviews 16 5 2012 * Spontaneous behaviors drive multidi-mensional, brainwide activity CStringer Science 364 255 2019 * Narrow-band blue-light treatment of seasonal affective disorder in adults and the influence of additional nonseasonal symptoms REStrong BKMarchant FWReimherr EWilliams PSoni RMestas Depress Anxiety 26 3 2009 * Neural circuit motifs in valence processing KMTye Neuron 100 2018 * Effects of diazepam and zolpidem on EEG beta frequencies are behaviour-specific in rats HVan Lier WHDrinkenburg YJVan Eeten AMCoenen Neuropharmacology 47 2004 * Newborn Brain Function Electroencephalography in Determining Mood in Animals Is Affected by Fetal Exposure to Maternal Serotonin Reuptake Inhibitors MVideman ATokariev HSaikkonen SStjerna HHeiskala OMantere SVanhatalo 10.1093/cercor/bhw153 Cerebral Cortex 153 2016 * Development of a Piglet Grimace Scale to Evaluate Piglet Pain 81. Using Facial Expressions Following Castration and Tail Docking: A Pilot Study AVViscardi MHunniford PLawlis MLeach PVTurner Front. Vet. Sci 2017, 4, 51 * Alcohol withdrawal in mice: Electroencephalographic and behavioral correlates DWWalker SZornetzer Electroencephalography and Clinical Neurology 36 1974 * The recent progress in animal models of depression Wang Prog. Neuro-Psychopharmacol. Biol. Psychiatry 77 2017 * The Student's Guide to Cognitive Neuroscience JWard 2015 Psychology Press Sussex 3rd Ed * LMWard Synchronous Neural Oscillations and Cognitive Processes 2003 7 * Circuit-based interrogation of sleep control FWeber Dan Y 10.1038/nature19773 Nature 538 2016 * Preliminary validation of natural depression in macaques with acute treatments of the fast-acting antidepressant ketamine XunxunChu Behavioural Brain Research 360 2019 * Abnormal early stages of task stimulus processing in children with attention-deficit hyperactivity disorder-evidence from event-related gamma oscillations JYordanova TBanaschewski VKolev WWoerner ARothenberger Clin. Neurophysiol 112 6 2001 * Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex LHZeng LXu DHGutmann MWong Ann. Neurol 63 2008